A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
This exciting opportunity is for a research technician to join the division of Hematology-Oncology at the Rogel Cancer Center, Michigan Medicine in Ann Arbor. The individual will join as a Research Lab Tech Senior in the Hematological Malignancies Program. He/she will be an integral member of a research team focused on myeloproliferative neoplasms (MPNs) and leukemia. Our laboratory focuses on pathophysiology of myelofibrosis and development of new therapies for myeloproliferative neoplasms and leukemia. We use cell line models, mouse models, primary clinical samples and patient derived xenografts (PDX) to identify new and novel therapeutic targets and biomarkers of disease.
This position is with a highly recognized PI who is well-funded. The candidate will be working in a collaborative, interdisciplinary, and highly translational environment. Motivated candidates who are interested in a career in oncology translational research will be most competitive for this position. Individuals with experience in animal handling, molecular and cell biology techniques such as but not limited to transplantable mouse models. flow cytometry, immunofluorescence, and gene knock-down and knock-out technologies are encouraged to apply. We are a collegial team and greatly support career advancement for all team members.
The successful candidate is required to function in the translational research laboratory and work independently or with minimal supervision. The role encompasses the following duties:
- Keep neat, detailed records, experimental protocols, and inventory of samples.
- Analyze and present data to team.
- Manage and maintain murine models of disease and conduct animal experiments with transplantable mouse models of MPN and leukemia.
- Follow up murine models with collection of mouse tissues, prepare samples for analysis and storage.
- Analyze samples by flow cytometry, cell isolation, colony assay, qRT-PCR, immunoblotting and other molecular biology techniques.
- Production of lentiviral and retroviral particles and transduction with these viruses in mouse and human cells.
- Participate in general lab communication, equipment maintenance, supplies, inventory, and organization.
Requirements for Research Lab Tech Senior:
Bachelor’s degree required and at least 2-3 years of experience in biomedical research. Candidate must have experience in mouse handling and good working knowledge of flow cytometry, cell culture techniques and molecular biology techniques such as PCR, cloning and immunoblotting. Proficiency with computers specifically MS Office (Excel, Word, and PowerPoint) and GraphPad Prism are also preferred. Ability to work independently and as part of a team while being collaborative in resolving problems.
Requirements for Research Lab Tech Intermediate:
HS Diploma with 1-3 years of research experience are required.
Candidates with Master’s degree or higher in biological sciences with >2 years of demonstrated research experience through publications are encouraged to apply. Additional experience in CRISPR/Cas9 and viral transduction, small molecule IC50 determination, and colony assays of hematopoietic cells is also a plus.
This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
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