The Division of Cardiovascular Medicine at the University of Michigan is expanding a nationally and internationally funded research program at the cutting edge of cardiovascular medicine. Led by Drs. Venkatesh Murthy and Sascha Goonewardena (whose work has appeared in leading journals including NEJM AI, JAMA, and Circulation) the program fuses artificial intelligence, advanced cardiac imaging, multiomics (proteomics, metabolomics, and genomics), and cardiometabolic disease biology to develop precision diagnostics and identify novel therapeutic approaches, with a particular focus on coronary microvascular disease and other cardiovascular conditions that disproportionately affect women and remain poorly served by existing diagnostic tools. This is a rare opportunity to join a high-impact, well-funded program doing science that matters.
This position serves as the proteomics and biospecimen technical lead for the program's cardiovascular biorepository and multi-omic assay operations. The incumbent will take senior technical ownership of the full biospecimen pipeline (from sample collection and biobanking through high-throughput proteomic assay coordination, quality control, and vendor management) and will develop and maintain the standard operating procedures that underpin all proteomic analyses. Close coordination with the clinical research coordinators and collaborating sites is central to the role.
- Lead biospecimen operations: receive, process, aliquot, and biobank plasma and other biospecimens collected during cardiac imaging visits; maintain cold chain and organized biorepository storage
- Coordinate, manage quality control for, and liaise with vendors for high-throughput proteomic assay operations, including manifest preparation, shipment logistics, and data receipt
- Develop, validate, and document standard operating procedures and quality-control criteria for biospecimen handling, assay preparation, and sample-to-data traceability
- Maintain accurate biospecimen inventory, sample tracking, and chain-of-custody records; keep electronic records synchronized and audit-ready
- Support proteomic data assembly and quality control in support of biomarker and signature analyses
- Coordinate closely with the Senior and Intermediate Clinical Research Coordinators and collaborating sites to ensure continuity and integrity of the proteomic workflow
- Support study operations under Good Clinical Practice (GCP) and IRB compliance requirements
- Maintain laboratory supplies, place orders, and operate and maintain equipment
- Contribute to manuscripts and reports under the direction of the Principal Investigator
- Other duties as assigned
- Bachelors degree in a biological or health science discipline
- Minimum 3 years of hands-on research experience in biospecimen processing, molecular biology, proteomics, or a closely related field
- Demonstrated experience with biospecimen processing and biobanking (plasma and serum) and preparation of samples for proteomic assays
- Demonstrated ability to develop, validate, and document standard operating procedures and to perform repeated procedures with precision and consistency
- Experience maintaining accurate records, sample tracking, and data quality control across multiple concurrent studies
- Strong organizational skills and attention to detail, with demonstrated ability to manage multiple concurrent workflows on schedule
- Ability to prepare and present clear written reports of work progress, assay results, and quality metrics
- Strong written and verbal communication skills, including ability to coordinate with clinical research coordinators and multi-site collaborators
- Understands and demonstrates the core concepts of Patient and Family Centered Care, including Respect and Dignity, Information Sharing, Participation, and Team Collaboration
- Advanced degree (MS or PhD) in a biological or health science discipline
- Experience with high-throughput proteomic platforms (Olink or SomaScan)
- Experience with LIMS systems, Good Clinical Practice (GCP), and IRB requirements for biospecimen-based research
- Familiarity with cardiac imaging research workflows or cardiovascular biorepository operations
- Background in cardiovascular biology, vascular biology, immunology, or cardiometabolic disease
- Experience with vendor coordination for outsourced assay services
- Record of contribution to peer-reviewed publications
- Experience coordinating with clinical research staff across multi-site programs
Work Schedule: Monday through Friday, standard business hours. This is an onsite position.
We, the staff and faculty of the U-M Cardiovascular Center (CVC) team, are committed to advancing medicine and serving humanity through living and teaching our core values of Respect and Compassion; Collaboration; Innovation; and Commitment to Excellence. Each CVC employee is expected to understand and demonstrate that in every in
