A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
The Biomedical Research Core Facilities (BRCF), as part of the Medical School's Office of Research (OoR), has an opening in the Transgenic Animal Model Core. The BRCF Transgenic Core was established in 1989 to provide access to transgenic animal technology in an efficient & effective manner. Researchers consult with the Core in all phases of genome editing, transgenic and gene targeting research from experimental design to mouse breeding. The Transgenic Core also offers a full suite of cryopreservation and assisted reproduction (IVF) services. The Core's mission is to provide access to complex technology that allows Principal Investigators to focus on their research instead of developing the tools for their research.
Provide support with assisted reproductive technology program including:
- In vitro fertilization of mouse eggs with mouse sperm.
- Cryopreservation of mouse sperm and embryos.
- Surgical transfer of embryos to surrogate female mice.
- Occasional weekend and weekly night work for superovulation treatment.
Assist with Molecular Biology Program:
- Perform methods including DNA purification, PCR reactions, and NGS library prep for genotype and CRISPR gRNA activity.
Animal Colony and Room Management
- Manage the mouse and rat transgenic production colonies
- Tissue collection and tagging for identification of mice and rats
- Weaning and distribution of mice and rats to on-campus and off-campus clients
- Superovulation for production of embryos for genetic manipulation.
- Postoperative care
- Inspection preparation and compliance to OSEH, AAALAC and IACUC
Provide customer service including communicating with clients about projects and animal breeding plans to maintain their animal colony strains used in their research; general laboratory maintenance
- Bachelor's degree
- 4-5 years of experience
- Demonstrated experience in molecular biology procedures such as DNA purification, PCR, molecular cloning, and NGS library preparation
- Demonstrated experience of highly organized record keeping
- Highly developed communication skills with people of diverse backgrounds
- Attention to detail, punctuality, and occasional weekend work required
- Ability to work independently with limited supervision as required
- Excellent interpersonal skills and ability to work with others in a collaborative environment
- Strong oral and written communication skills
- Proficient in Microsoft office software
Previous experience either working in a transgenic core or in a laboratory that has used transgenic rodents in research. Demonstrated experience working with mice and rats. Demonstrated experience in tissue cell culture.
The Michigan Medicine Biomedical Research Core Facilities are firmly committed to advancing Inclusion, Diversity, Equity, Accessibility, and Belonging which are core values at the Office of Research. Our community supports recruiting and cultivating a diverse workforce, as it is a reflection of our commitments to serve the diverse people of Michigan and the world. We strive to create a work culture where every team member feels respected, valued, and safe.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
