ROLE DESCRIPTION: The Scientist / Senior Scientist in bacterial Bioprocess Development plays an essential role in the Zoetis vaccine and biopharmaceutical strategies for veterinary medicine. The successful applicant will work as a senior team member in the development of fermentation and bioreactor protocols in support of global product development and GMP (Good Manufacturing Practice) manufacture of biological veterinary products. The incumbent is expected to work hands-on at the bench while providing strong technical leadership to project teams within the discipline of biological manufacturing science. The Scientist / Senior Scientist is expected to work with a high degree of autonomy in the discipline and work on project teams in collaboration and partnership with colleagues in downstream process development, formulation development, and bioanalytical science. To be successful, they will have advanced knowledge of multiple platforms for cultivation of wild type micro-organisms and host prokaryotic systems for expression of recombinant proteins such as protein expression in prokaryotic or yeast hosts. They will serve as a technical resource within the line and will have a working knowledge of related bioprocessing unit operations such as cell line development, seed banking, and protein purification techniques including chromatography and membrane processing. The position is based in Kalamazoo (Michigan, USA) with frequent interactions with colleagues and external partners located around the globe. RESPONSIBILITIES: The major duties will include but are not limited to: * Independently apply an advanced knowledge of biological manufacturing science in the design and execution of bioreactor experiments to identify and validate critical parameters that affect upstream and downstream bioprocess performance across multiple scales. The parameters to be investigated include reactor configuration, medium formulation, and fed-batch strategies. * Systematically optimize the parameters that affect bioreactor performance through the application of statistical models for experimental design and analysis. * Perform and support antigen purification and/or concentration processes to support mono- and multivalent vaccine development. * Work in collaboration with colleagues in pilot and manufacturing scale operations to devise scale-up strategies for fermentation processes. Provide technical leadership in scale up programs based on risk assessment of critical parameters and their impact on product quality attributes. * Contribute as an expert team member towards the supervision of bioprocess development work programs performed by contract development and manufacturing organizations. * Serve as a technical resource to project teams by providing the essential expertise in biological manufacturing science required for successful project delivery. This includes a willingness to share experimental findings with team members, peers, and management Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at site, or (2) via email to/from addresses using only the Zoetis domain of @zoetis.com . In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis..
Employer's Job# JR00006059
Please visit job URL for more information about this opening and to view EOE statement..
