All application materials should be submitted through the Interfolio Portal: https://apply.interfolio.com/174339
Application deadline 7/1/2026
To apply, please submit the following materials:
- Cover letter specifying the preferred tenure home unit (College of Pharmacy or Medical School) and how their expertise aligns with the AI/ML drug discovery focus areas.
- Curriculum vitae.
- Statement of research interests and vision (2-3 pages).
- Statement of teaching philosophy and mentoring approach (1-2 pages).
- Names and contact information for three references.
For informal inquiries, please contact the search committee chair, Dr. Duxin Sun ([email protected])
The University of Michigan (U-M) invites applications for three tenure-track faculty positions in the area of Artificial Intelligence (AI) and Machine Learning (ML) in Drug Discovery. This is a unique cluster hire initiative spanning the College of Pharmacy, Life Sciences Institute (LSI), and Medical School, with support from the Office of the Provost. We are particularly seeking mid-career candidates who would meet University of Michigan criteria for appointment as associate professor or professor with tenure, and who have strong records of research excellence in AI/ML-driven approaches to drug discovery. Successful candidates will be appointed in the unit most aligned with their expertise, with the expectation of fostering interdisciplinary collaborations across the university. Joint appointments may be considered on a case-by-case basis. The successful candidates may also take a leadership role in the newly launched Institute for AI-Driven Therapeutics Discovery (AI-Tx), which received support from the University of Michigan Impact Institutes Initiative.
Strategic Impact and Vision
Drug development faces significant challenges, including high costs, long timelines, and a 90% failure rate in clinical trials. AI and ML have the potential to enhance drug discovery by improving the identification of disease and drug targets, accelerating the identification of drug candidates, optimizing the design of therapeutics, and guiding predictions of clinical outcomes. The goal of this cluster hire is to advance U-M?s leadership in drug discovery by integrating cutting-edge AI and ML methodologies into the drug discovery process, enhancing efficiency, reducing failure rates, and supporting therapeutic innovation.
This cluster hire aligns with U-Ms Look to Michigan strategic plan, emphasizing:
- Research Innovation: Advancing AI/ML methodologies for drug discovery and improving therapeutic success rates.
- Interdisciplinary Collaboration: Strengthening connections between computational and experimental drug development experts.
- Economic and Societal Impact: Translating discoveries into startup ventures and industry partnerships to drive drug commercialization.
- Education and Workforce Development: Training the next generation of scientists in AI/ML-enabled drug development.
Responsibilities
Resources and Collaborative Environment
U-M provides an exceptionally collaborative and resource-rich environment for AI/ML and drug discovery research, including:
- Institute of AI-driven therapeutics discovery (AI-Tx). UM just launched AI-Tx with a goal to integrate AI and machine learning to address root causes of drug development failures, aiming to revolutionize the discovery of small molecules and biologics and position UM as a global leader in this field.
- Michigan Drug Discovery (MDD): A hub for academic-industry partnerships, drug screening, medicinal chemistry, and translational research.
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