A fully funded postdoctoral position is immediately available Mark Hatley's laboratory in the Molecular Oncology Division of the Department of Oncology at St. Jude Children's Hospital. The Hatley lab studies how normal development processes are perturbed to drive pediatric embryonal tumors using rhabdomyosarcoma as a model system. Our recent findings defined the cell of origin of rhabdomyosarcoma, a presumed skeletal muscle tumor, as an endothelial progenitor cell (Cancer Cell, 33:108-124, 2018). We now seek to elucidate the mechanism of this cell reprogramming event and its role in cell transformation. The lab leverages genetically engineered mouse models, patient-derived xenografts, human and mouse tumor and primary cell lines as well as induced pluripotent stem cells as model systems to interrogate the underlying pathobiology of pediatric rhabdomyosarcoma.
The Hatley lab is a very collaborative, interactive environment focused on scientific and career development of trainees. The lab supports a healthy work/life balance and diversity with a focus on career development. Dr. Hatley was the 2019 mentor of the year at St. Jude. Successful applicants should have strong organizational and communication skills with drive and dedication to participate as a member of our team.
The ideal candidate should have just received their PhD or have less than one year of postdoctoral research. Experience in mouse models, cell biology, and molecular biology is preferred. Please send a cover letter describing research interests and accomplishments, CV and the names and addresses of three references to .
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